Liverpool secured a vital 1-0 away win at Sunderland on Wednesday night to move within three points of the top four, but the victory came at a massive cost.
Wataru Endo, playing as a makeshift right-back, was stretchered off with a "serious" ankle injury.
With Conor Bradley and Jeremie Frimpong already sidelined, Arne Slot has now used six different players at right-back this season.
Slot admitted the situation is "bleak" ahead of their weekend FA Cup clash at Nottingham Forest.