Liverpool's Uruguayan striker has undergone knee surgery and is hoping to be fit in time to face England on 19th June.
"Everybody is obviously disappointed for Luis, people that know him – maybe not us – because he is a big player for Uruguay," said Henderson.
“I gave him a text to see if he is doing all right and wished him good luck with whatever he has got to have done.
“But I am sure, knowing the type of person he is, he is a fighter and I am sure come maybe the first game or the second game in the World Cup, I am sure he will be ready and raring to go.”