The Reds currently have six players out with hamstring problems after Philippe Coutinho and Dejan Lovren were forced off during the 1-0 win at Stoke on Tuesday night.
The duo join a lengthy list of Liverpool players out with hamstring injuries, which includes Divock Origi, Martin Skrtel, Jordan Rossiter and Daniel Sturridge.
Statistics suggest Liverpool are running an average of six kilometres more during matches under Klopp than when Brendan Rodgers was in charge and completing more sprints per game.
Klopp is renowned for his intense training methods and high-energy style of play but chartered physiotherapist Sammy Margo believes that approach could now be hurting the Liverpool squad.
"The instalment of the new manager is really relevant because hamstring injuries are often due to overloading, to pushing too hard," Margo said.
"There's no way it's a coincidence. Maybe two or three hamstring strains but when it's six, it's not a coincidence.
"A lot of clubs have injuries at this time of year but at Liverpool they all have similar injuries and when you have several players with similar injuries you have to look at the training.
"A large per cent of injuries are brewing during training and then break out during matches.
"They need to look at the training and change their attitude and approach. Otherwise it will keep happening."
Liverpool have 10 players out in total with Mamadou Sakho (knee), Jordan Henderson (heel), Joe Gomez (knee) and Danny Ings (knee) on the sidelines.
The Capital One Cup semi-final on Tuesday was the Reds' fifth game in 17 days and Margo believes the busy schedule is also a factor in the club's fitness problems.
"Football does need a break at this time of year," said Margo, who became the English league's first female physio during a stint at Barnet.
"It's cold, it's intensive, they've been playing many matches back-to-back and at some point they need a break.
"These guys are young, they're fit, they can recover quickly but even with those factors and an amazing medical team they're still struggling.
"Combine that with the increased intensity from a new manager and it's no surprise they're having problems."
Source: PA