The first leg will be played at Anfield on 10th March, with the second leg at Old Trafford the following Thursday.
Full draw
Shakhtar Donetsk v Anderlecht
Basel v Sevilla
Villarreal v Bayer Leverkusen
Athletic Bilbao v Valencia
Liverpool v Manchester United
Sparta Prague v Lazio
Borussia Dortmund v Tottenham
Fenerbahce v Braga