Liverpool have played Anderlecht twice before in European competition, in the second round of the 1964/1965 Champions Cup, winning both legs - 3-0 at Anfield and 1-0 in Belgium.
Anderlecht have hosted English clubs on 13 occasions, winning seven, drawing teice and losing four times. Their last match at home to an English club was against Leeds United in February 2001, which they lost 4-1.
Anderlecht's last home victory against an English club was in October 2000 when they beat Manchester United 2-1.
Liverpool have visited Belgium on three occasions, winning twice and drawing once. They won 1-0 at Anderlecht in 1964, 2-1 at Standard Liege in 1965 and drew 1-1 at Brugges in the Uefa Cup Final in 1976.
Liverpool have never been beaten by a Belgian club in seven European matches. Anderlecht have been eliminated by an English club on seven occasions.