Liverpool will be without Steven Gerrard (groin), Steve Finnan (knee), Chris Kirkland (finger) and Milan Baros (broken leg).
Michael Owen travelled with the squad and is expected to be on the bench for the game at Stamford Bridge.
Jamie Carragher returned to action after recovering from a broken leg, but will not be match fit for a couple more weeks.
Predict the score on LFC Online's football forum.