If the Reds are to beat Spurs, Man City and Aston Villa to the final Champions League qualifying spot then they will need to win all their remaining league games according to Mascherano.
"I think we will have to win all our games. We have seven finals and we have to win all of them to have hope of finishing fourth," said the Argentina captain.
"If we can win 21 points, maybe we will be there. If not, it will be very difficult."