Reina has yet to keep a clean sheet this season and made a couple of big mistakes in the derby defeat. However, Reina has the full confidence and support of his manager.
"I have a lot of confidence in Pepe Reina and he is a very good goalkeeper," said Rafa Benitez.
"Pepe kept 33 clean sheets last season and was fantastic. I was talking with him after the game on Saturday and he felt he could have done something more about the first two goals but I said 'no' because we didn't defend well. The third goal was a mistake and he knows it was.
"We need to improve in defence, that is very clear, and it's good that after Saturday's defeat we have a game against PSV Eindhoven so we can put things right."