A win is a must (will win?) for Liverpool who will see it as an excellent opportunity to stake a claim for second spot in the group as rivals Basle welcome table toppers Valencia.
At present Group B is delicately poised, with Liverpool finding themselves in four points alongside FC Basle, with a trip to the Swiss Champions' St Jakob Stadium yet to come.
Spartak go into the game third in the Russian Championship and on the back of a 4-0 win over Uralan.