"I don't like to talk about losing. I prefer to talk about this being a good opportunity for us to change things," said the Reds' boss.
"It's a long race and we know just how difficult it is to beat the top sides, but we must also remember that we will play all of them at home in the second half of the season. We need to remember that we will still have our chance.
"The players know how important this game is. I think it could be a starting point for us to change things, especially with our record away from home. We want to go to Old Trafford to show people that we can beat them.
"If you're talking about one game, then anything can happen. If you're talking about the league, we know we are not playing to our normal level but I'm sure we will improve and I have confidence that we will be there at the end of the season."