"We can't think about anything else but beating Manchester United on Saturday," said Kuyt.
"United are a very good team, but we have shown this season that we can beat the big opponents when they come along.
"We won away to Chelsea and Real Madrid, we beat United and Madrid at Anfield so I think we can do something on Saturday.
"It will difficult, we know that. United are playing really well, especially at home, but we will give it all we can and try to win because we have to take three points.
"We have just beaten Real Madrid and are very confident. We'll give it a try and it will be difficult but we are playing well and anything can happen."