Liverpool took the lead through Robbie Fowler, his first European goal for the club since a qualifier against FC Haka in 2001, but two goals in four minutes put Galatasary in charge of the game before half time.
Galatasary added a third in the second half before Robbie Fowler narrowed the gap in the final minute when he headed home a Jermaine Pennant cross.
Although the result was disappointing, the game was played like a pre-season friendly and there won't be too many inquests into the team's performance.