Salif Diao is suspended for the trip to St Mary's and, with Dietmar Hamann still ruled out with a shin injury, John Arne Riise could play in midfield, with Djimi Traore returning as left-back.
Michael Owen and Emile Heskey are expected to lead the attack, with Neil Mellor on the bench.
Team (from): Kirkland, Carragher, Henchoz, Hyypia, Traore, Riise, Murphy, Gerrard, Cheyrou, Smicer, Biscan, Diouf, Heskey, Owen, Baros, Mellor, Dudek, Xavier, Babbel.
