Jamie Carragher and Steve Finnan played in the reserves' midweek win over Everton, but are unlikely to figure on Saturday.
El Hadji Diouf has joined up with the Senegal squad for the African Nations Cup, while Milan Baros is still recovering from a broken leg.
Paul Jones will continue in goal, in the absence of Chris Kirkland and Jerzy Dudek.
Freddie Kanoute has opted to join up with Mali rather than play for his club, but Michael Brown could make his debut after his £500,000 move from Sheffield United.